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CDK2 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase 2
Descriptor
Spanish
:
Quinasa 2 Dependiente de la Ciclina
Descriptor
Portuguese
:
Quinase 2 Dependente de Ciclina
Synonyms
English
:
CDK2 Protein
Cdc2-Related Protein Kinase
p33cdk2 Kinase
Cdc2 Related Protein Kinase
Cyclin Dependent Kinase 2
Cdk2 Protein Kinase
Tree Number:
D08.811.913.696.620.682.700.646.500.750
D12.644.360.250.323
D12.776.167.200.323
D12.776.476.250.323
Definition
English
:
A key regulator of
CELL CYCLE
progression. It partners with
CYCLIN E
to regulate entry into
S PHASE
and also interacts with
CYCLIN A
to phosphorylate
RETINOBLASTOMA PROTEIN
. Its activity is inhibited by
CYCLIN-DEPENDENT KINASE INHIBITOR P27
and
CYCLIN-DEPENDENT KINASE INHIBITOR P21.
History Note
English
:
2006(1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50714
Unique Identifier:
D051357
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS